Isotopically Labeled Compounds
Medchemexpress LLC Escitalopram-d6 oxalate | 1217733-09-9 | C22H17D6FN2O5 | 1 MG
Escitalopram-d6 oxalate is a deuterium-labeled form of Escitalopram oxalate, a selective serotonin reuptake inhibitor (SSRI) with high binding affinity and selectivity. It is an antidepressant used in research for major depression. Deuterium-labeled compounds are valuable as tracers and internal standards in drug development and quantitative analysis.
- Deuterium labeled compound
- Functions as a selective serotonin reuptake inhibitor (SSRI)
- Applicable as a tracer in research
- Suitable as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Used for major depression research
- Contains stable heavy isotopes for drug development quantitation
Medchemexpress LLC Ranolazine-d3 | 1054624-77-9 | 99.5% | 100 MG
Ranolazine-d3 is a deuterium labeled anti-angina agent that inhibits the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure. It also functions as a partial fatty acid oxidation inhibitor and is intended for research use only.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC D-Glucose-d4 | 478529-49-6 | 99.0% | 50 MG
D-Glucose-d4 is the deuterium-labeled form of D-Glucose, an important monosaccharide and carbohydrate in biology. It serves as a critical signaling molecule and component of general metabolism. This compound can be utilized as a tracer and as an internal standard for quantitative analysis methods like NMR, GC-MS, or LC-MS.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Cefoperazone-d5 | 2410425-70-4 | 98.6% | 100 UG
Cefoperazone-d5 is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during drug development.
- Deuteration is noted for its potential to impact the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Pimobendan-d3 | 74150-27-9 | 99.4% | 50 MG
Pimobendan-d3 (UD-CG115-d3) is deuterium labeled Pimobendan. It is a selective inhibitor of PDE3 with an IC50 of 0.32 μM. Deuterium labeled compounds are used as tracers for quantitation during drug development due to their potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- For research use only
Medchemexpress LLC Norgestrel-d6 | 2376035-98-0 | 99.5% | 5 MG
Norgestrel-d6 is the deuterium labeled Levonorgestrel, a synthetic progestogen used as an active ingredient in some hormonal contraceptives. It functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It is intended for research use only and can serve as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled Levonorgestrel
- Synthetic progestogen
- Click chemistry reagent
- Contains an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- For use as a tracer or internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Naratriptan-d3 hydrochloride | 1190021-64-7 | 1 MG
Naratriptan-d3 is a deuterium labeled form of Naratriptan hydrochloride, a selective 5-HT1B/1D receptor agonist. This compound is peripherally active and exhibits good oral bioavailability, inducing cranial artery vasoconstriction. It also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation, making it suitable for research into acute migraine, targeting cranial vascular and neuroinflammatory mechanisms.
- Used as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Acts as a selective 5-HT1B/1D receptor agonist
- Exhibits good oral bioavailability
- Induces cranial artery vasoconstriction
- Inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation
- Reduces sterile inflammation
Cambridge Isotope Laboratories 1-BROMOBUTANE (D9, 98%), 5 G, 98195-36-9
1-BROMOBUTANE (D9, 98%), 5 G, 98195-36-9
Cambridge Isotope Laboratories Docosanoic acid (1 2 3 4 5 6-13C6 99%) CP 95% 5 mg
Docosanoic acid (1 2 3 4 5 6-13C6 99%) CP 95% 5 mg
Cambridge Isotope Laboratories 5-Methoxytryptamine HCl (A A B B-D4 98%) 0 1 g
5-Methoxytryptamine HCl (A A B B-D4 98%) 0 1 g